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A cell-permeable purine compound that binds ARFGAPs (Kd = 364 and 620 nM for AMAP1 and ARFGAP1, respectively) and acts as a broad specificity ARFGAPs inhibitor (GTPase activating proteins of ADP-ribosylation factor).
The PknG Inhibitor, also referenced under CAS 329221-38-7, controls the biological activity of PknG. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
CFTR Inhibitor II, GlyH-101, CAS 328541-79-3, is a cell-permeable potent, selective and reversible open-channel blocker of CFTR (Ki = 4.3 μM in CFTR-expressing FRT cells).
PP2, CAS 172889-27-9, is a potent, reversible, ATP-competitive, inhibitor of the Src family of protein tyrosine kinases (IC50 = 4, 5, 5, & 100 nM for p56lck, p59fynT, Hck, & Src, respectively).
The REV-ERB Agonist II, SR9009 controls the biological activity of REV-ERB. This small molecule/inhibitor is primarily used for Biochemicals applications.
The InSolution™ AMPK Inhibitor, Compound C·2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
The β-Catenin/Tcf Inhibitor V, BC21, also referenced under CAS 691005-38-6, controls the biological activity of β-Catenin/Tcf. This small molecule/inhibitor is primarily used for Biochemicals applications.
The InSolution™ Casein Kinase I Inhibitor, D4476 controls the biological activity of Casein Kinase I. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.